Rota viral infection: a significant disease burden to Libya

Alkoshi, Salem, Ernst, Kacey, Maimaiti, Namaitijiang and Dahlui, Maznah, (2014). Rota viral infection: a significant disease burden to Libya. Iranian Journal of Public Health, 43(10), 1356-1363

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  • Sub-type Journal article
    Author Alkoshi, Salem
    Ernst, Kacey
    Maimaiti, Namaitijiang
    Dahlui, Maznah
    Title Rota viral infection: a significant disease burden to Libya
    Appearing in Iranian Journal of Public Health
    Volume 43
    Issue No. 10
    Publication Date 2014-10-22
    Place of Publication Tehran
    Publisher Tehran University of Medical Sciences
    Start page 1356
    End page 1363
    Language eng
    Abstract

    Background: Rotavirus is a common infection causing 450,000 deaths annually primarily in children 5
    years and below. Despite the high burden of disease, little is known about the epidemiology of rotavirus
    in Libya. The aim of this study was to estimate the rotavirus disease burden among Libyan children.
    Methods: A cross-sectional study was carried out prospectively among children 5 years old and below
    between August 2012 and April 2013. Stool samples of children with diarrhea attending the outpatient
    department or admitted to the pediatric wards, at three public hospitals within the northwestern region
    of Libya were tested for rotavirus. The seasonality, symptomology demographics and outcomes of rotavirus
    cases were determined and compared to other diarrhea illnesses. An estimated incidence rate per
    100,000 children aged 5 years and below was determined.
    Results: A total of 545 children with diarrhea were identified for participation. Results of rotavirus immunoassays
    determined 57% of cases were caused by rotavirus. Inpatients were more likely to be rotavirus
    positive than outpatients (58% vs. 53%, P<0.05), Most rotavirus positive cases (86%) were found
    among children below 2 years of age. Rotaviral cases peaked in the winter, constituting 76% of diarrheal
    illness in February and very few rotavirus cases in the summer months. The incidence rate of rotavirus
    diarrhea was estimated at 640/100,000 children aged 5 years and below.
    Conclusion: Rotavirus infection poses a significant disease burden in Libya. Preventive measures such as
    proper hygiene should be emphasized. Introduction of vaccination against rotavirus into the national
    immunization program should be examined, as it would likely be a cost-effective investment.

    Keyword Rotavirus
    Diarrhea
    Burden
    Libya
    Children
    Incidence
    Copyright Holder Iranian Journal of Public Health
    Copyright Year 2014
    Copyright type All rights reserved
    ISSN 22516093
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    Created: Tue, 29 Sep 2015, 12:33:52 JST