Environmental arsenic epidemiology in the Mekong River basin of Cambodia

Kongkea, Phan, Kim, Kyoung-Woong and Hashim, Jamal H., (2014). Environmental arsenic epidemiology in the Mekong River basin of Cambodia. Environmental Research, 135 37-41

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  • Sub-type Journal article
    Author Kongkea, Phan
    Kim, Kyoung-Woong
    Hashim, Jamal H.
    Title Environmental arsenic epidemiology in the Mekong River basin of Cambodia
    Appearing in Environmental Research
    Volume 135
    Publication Date 2014
    Place of Publication Online
    Publisher Elsevier
    Start page 37
    End page 41
    Language eng
    Abstract

    We investigated relationship of arsenicosis symptoms with total blood arsenic (BAs) and serum albumin (SAlb) of residents in the Mekong River basin of Cambodia. We found that arsenicosis patients had significantly higher BAs and lower SAlb than asymptomatic villagers (Mann-Whitney U test, p < 0.01). Arsenicosis symptoms were found to be 76.4% (1.764 times) more likely to develop among individuals having an SAlb ≤ 44.3 g L-1 than among those who had an SAlb > 44.3 g L-1 (OR = 1.764, 95% CI = 0.999 – 3.114) and 117.6% (2.176 times) as likely to occur among those with BAs > 5.73 µg L-1 than for those having BAs ≤ 5.73 µg L-1 (OR = 2. 176, 95% CI = 1.223 – 3.872). Furthermore, a significant negative correlation was also found between BAs and SAlb (rs (199) = - 0.354, p < 0.0001). As such, this study suggests that people with low SAlb and/or high BAs are likely to rapidly develop arsenicosis symptoms.

    Keyword Arsenicosis
    Blood arsenic
    Urinary arsenic
    Serum albumin
    Cambodia
    Copyright Holder Elsevier
    Copyright Year 2014
    Copyright type All rights reserved
    ISSN 00139351
    DOI 10.1016/j.envres.2014.07.031
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