Skeletal-Related Events among Breast and Prostate Cancer Patients: Towards New Treatment Initiation in Malaysia's Hospital Setting

Puteh, Sharifa Ezat Wan, Aljunid, Syed M., Khamis, Noraziani, Ahmed, Zafar, Nur, Amrizal M., Aizuddin, Azimatun N., Ismail, Fuad, Abdullah, Norlia, Zainuddin, Zulkifli Md., Kassim, Abdul Yazid Mohd, Haflah, Nor Hazla Mohamed and Sulong, Saperi, (2013). Skeletal-Related Events among Breast and Prostate Cancer Patients: Towards New Treatment Initiation in Malaysia's Hospital Setting. Cancer Prevention, 14 3357-3362

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  • Sub-type Journal article
    Author Puteh, Sharifa Ezat Wan
    Aljunid, Syed M.
    Khamis, Noraziani
    Ahmed, Zafar
    Nur, Amrizal M.
    Aizuddin, Azimatun N.
    Ismail, Fuad
    Abdullah, Norlia
    Zainuddin, Zulkifli Md.
    Kassim, Abdul Yazid Mohd
    Haflah, Nor Hazla Mohamed
    Sulong, Saperi
    Title Skeletal-Related Events among Breast and Prostate Cancer Patients: Towards New Treatment Initiation in Malaysia's Hospital Setting
    Appearing in Cancer Prevention
    Volume 14
    Publication Date 2013
    Place of Publication Goyang
    Publisher Asian Pacific Organization for Cancer Prevetion
    Start page 3357
    End page 3362
    Language English
    Abstract The human skeleton is the most common organ to be affected by metastatic cancer and bone metastases are a major cause of cancer morbidity. The five most frequent cancers in Malaysia among males includes prostate whereas breast cancer is among those in females, both being associated with skeletal lesions. Bone metastases weaken bone structure, causing a range of symptoms and complications thus developing skeletal-related events (SRE). Patients with SRE may require palliative radiotherapy or surgery to bone for pain, having hypercalcaemia, pathologic fractures, and spinal cord compression. These complications contribute to a decline in patient healthrelated quality of life. The multidimensional assessment of health-related quality of life for those patients is important other than considering a beneficial treatment impact on patient survival, since the side effects of treatment and disease symptoms can significantly impact health-related quality of life. Cancer treatment could contribute to significant financial implications for the healthcare system. Therefore, it is essential to assess the health-related quality of life and treatment cost, among prostate and breast cancer patients in countries like Malaysia to rationalized cost-effective way for budget allocation or utilization of health care resources, hence helping in providing more personalized treatment for cancer patients.
    Keyword Skeletal related events
    Bone metastases
    Quality of life
    Breast cancer
    Prostate cancer
    Cost
    Copyright Holder The Authors
    Copyright Year 2013
    Copyright type Creative commons
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    Created: Wed, 11 Jun 2014, 16:20:10 JST